Johanna F Dekkers Selected Research

Colforsin

1/2020	Protocol for Application, Standardization and Validation of the Forskolin-Induced Swelling Assay in Cystic Fibrosis Human Colon Organoids.
1/2020	Forskolin-induced swelling of intestinal organoids correlates with disease severity in adults with cystic fibrosis and homozygous F508del mutations.
1/2018	Stratifying infants with cystic fibrosis for disease severity using intestinal organoid swelling as a biomarker of CFTR function.
7/2013	A functional CFTR assay using primary cystic fibrosis intestinal organoids.

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Johanna F Dekkers Research Topics

Disease

12	Cystic Fibrosis (Mucoviscidosis) 01/2020 - 01/2013
3	Breast Neoplasms (Breast Cancer) 01/2021 - 01/2020
3	Neoplasms (Cancer) 01/2020 - 01/2019
1	Stomach Neoplasms (Stomach Cancer) 11/2021
1	Neuroblastoma 10/2020
1	Neoplasm Metastasis (Metastasis) 01/2019
1	Lung Neoplasms (Lung Cancer) 01/2019
1	Respiratory Syncytial Virus Infections 01/2019
1	Exocrine Pancreatic Insufficiency 01/2018
1	Infections 11/2015
1	Rotavirus Infections 11/2015

Drug/Important Bio-Agent (IBA)

7	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 01/2018 - 01/2013
4	ColforsinIBA 01/2020 - 07/2013
3	Estrogen ReceptorsIBA 01/2021 - 01/2020
3	Pharmaceutical PreparationsIBA 12/2019 - 07/2013
2	Proteins (Proteins, Gene)FDA Link 01/2019 - 01/2018
1	B7-H1 AntigenIBA 11/2021
1	Progesterone Receptors (Progesterone Receptor)IBA 01/2021
1	Fluorescent Dyes (Fluorescent Probes)IBA 10/2020
1	dinutuximabIBA 10/2020
1	palbociclibIBA 01/2020
1	venetoclaxIBA 01/2020
1	Fulvestrant (Faslodex)FDA Link 01/2020
1	Phenobarbital (Luminal)FDA Link 01/2020
1	Cyclin-Dependent Kinase 4IBA 01/2020
1	TrypsinogenIBA 01/2018
1	Pancreatitis-Associated ProteinsIBA 01/2018
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2016
1	ivacaftorIBA 01/2016
1	Antiviral Agents (Antivirals)IBA 11/2015
1	RNA (Ribonucleic Acid)IBA 11/2015
1	AnionsIBA 07/2013
1	lumacaftorIBA 07/2013
1	NucleotidesIBA 07/2013

Therapy/Procedure

6	Therapeutics 01/2020 - 07/2013
1	Heterologous Transplantation (Xenotransplantation) 01/2021
1	Transplantation 01/2020
1	Drug Therapy (Chemotherapy) 01/2020
1	Mammaplasty (Breast Reconstruction) 01/2020
1	Precision Medicine 07/2013